GAN ZHAO LAB · XIAMEN UNIVERSITY

Research

Decoding the cellular logic of lung injury and regeneration.

01 / Pulmonary vascular repair

Repairing the pulmonary microcirculation

We study endothelial survival, proliferation, lineage plasticity and molecular signaling during vascular reconstruction following lung injury, including the TGF-βR2 and COUP-TF2 pathways.

02 / Epithelial regeneration

Restoring functional alveoli

Our work explores alveolar epithelial progenitors, regeneration-associated niches and the coordination of epithelial and stromal programs during injury resolution.

03 / Immunity & delivery

Controlling inflammation to enable repair

We investigate endothelial–immune interactions such as SPARCL1 signaling and explore cell-targeted lipid nanoparticle approaches for modulating lung injury responses.